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In models of Alzheimers disease, supplementation with coenzyme Q10 and lipoic acid improved ATP production and superoxide dismutase levels, while decreasing apolipoprotein E and amyloid-beta fragments, as well as reducing phosphorylated tau and neuroinflammation

In summation, GGCs potential to elevate intracellular glutathione levels above homeostasis in an energy-efficient manner, makes it a promising candidate as a potential therapeutic for mitochondrial diseases

2003;38:745750 Deugnier Y, Jouanolle AM, Chaperon J, Moirand R, Pithois C, Meyer JF, et al

Exogenous GSH application were further enhanced the expression levels of GSH (3.74-fold), GST (6.19-fold), GR (2.66-fold) in roots (Fig